Cryo 21 facilitates a thermal shock by reducing the temperature of fat cells, causing them to die off in a natural called apoptosis.  This process causes a gradual degeneration and evacuation of fat cells.  Apoptosis occurs when the machine reduces the temperature in the treatment area anywhere from 46 degrees F to 17 degrees F without the client feeling cold or discomfort.  After 4-6 treatments it is not unusual for clients to loose up to 5 inches around the waist or up to 5 dress sizes.